credentials


Ph.D, 2010, Neuroscience, New York University, New York, NY
B.A., 2005, Neuroscience, Vassar College, Poughkeepsie, NY

publications


Cowansage K, Shuman T, Dillingham B., Chang A, Golshani P & Mayford M. (2014). Direct reactivation of a coherent neocortical memory of context. Neuron, In Press. PMID: 25308330 Cowansage K, Bush DEA, Josselyn S, Klann E & LeDoux JE (2013). Basal variability in CREB phosphorylation predicts trait-like differences in amygdala-dependent memory. Proc Natl Acad Sci. 110(41): 16645-50. PMID 24062441. Hoeffer CA, Wong H, Cain P, Levenga J, Cowansage K, Choi Y, Davy C, Majmundar N, McMillan DR, Rothermel B & Klann E (2013). Regulator of Calcineurin 1 (RCAN1) Modulates Expression of Innate Anxiety and Anxiogenic Responses to Selective Serotonin Reuptake Inhibitor (SSRI) Treatment. J Neurosci. 33(43): 16930-44. PMID 24155299. Sanders J, Cowansage KK, Baumgärtel K, Mayford M (2012). Elimination of dendritic spines with longterm memory is specific to active circuits. J Neurosci. 32(36): 12570-8. Pubmed PMID: 22956846. Kaphzan H, Hernandez P, Jung JI, Cowansage KK, Deinhardt K, Chao MV, Abel T, Klann E (2012). Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors. Biol Psychiatry. 72(3): 182-90. Pubmed PMID: 22381732 Hoeffer CA*, Cowansage KK*, Arnold EC, Banko JL, Moerke NJ, Rodriguez R, Schmidt EK, Klosi E, Chorev M, Lloyd RE, Pierre P, Wagner G, Ledoux JE, Klann E (2011). Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proc Natl Acad Sci. 108(8): 3383-3388. NIHMSID277364. *Authors contributed equally Cowansage KK, LeDoux, JE & Monfils M-H. (2010). BDNF: A dynamic gatekeeper to plasticity. Cur Mol Pharmacol. 3(1): 12-29. (Review) PubMed PMID: 20030625 Monfils, M-H; Cowansage, KK; Klann, E & LeDoux, JE (2009) Behavioral blockade of reconsolidation prevents return of fear. Science. 324 (5929): 951-5. NIHMSID277365. Monfils, M-H; Cowansage, KK; LeDoux, JE. (2007). BDNF: linking fear learning to memory consolidation. Mol Pharmacol 72(2): 235-7. (Review) PubMed PMID: 17522182. Marchand, C; Johnson, AA; Karki, RG; Pais, GC; Zhang, X; Cowansage, K; Patel, TA; Nicklaus, MC; Burke, TR Jr; Pommier, Y (2003). Metal-dependent inhibition of HIV-1 integrase by β-diketo acids and resistance of the soluble double mutant, (F185K/C280S), Mol Pharmacol. 64 (3): 600-609. PubMed PMID:12920196 Marchand, C; Zhang, X; Pais, GC; Cowansage, K; Neamati, N; Burke, TR Jr; Pommier, Y. (2002). Structural determinants for HIV-1 integrase inhibition by beta-diketo acids, J Biol Chem 277 (15): 12596-12603. PubMed PMID:11805103 Pais, GC; Zhang, X; Marchand, C; Neamati, N; Cowansage, K; Svarovskaia, ES; Pathak, VK; Tang, Y; Nicklaus, M; Pommier, Y; Burke, TR Jr. (2002). Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors, J Med Chem 45 (15): 3184-3194. PubMed PMID:12109903 Neamati, N; Lin, Z; Karki, RG; Orr, A; Cowansage, K; Strumberg, D; Pais, GC; Voigt, JH; Nicklaus, MC; Winslow, HE; Zhao, H; Turpin, JA; Yi, J; Skalka, AM; Burke, TR Jr; Pommier; Y. (2002). Metal dependent inhibition of HIV-1 integrase, J Med Chem 45 (26): 5661-5670. PubMed PMID:12477350.

Abstracts, Invited Talks & Contributions


Cowansage K (Dec. 2014). Workshop in Memory of Rita Levi-Montalcini. European Brain Research Institute (EBRI). Rome, Italy.
Cowansage K & Mayford M (2013). Downstream circuit analysis of an optogenetically reactivated memory. Society for Neuroscience Abstracts, 190.13, San Diego, CA.
Cowansage K (2013). Invited Talk. Genetic tracking and manipulation of active neural circuits. Society for Neuroscience Minisymposium, San Diego, CA.
Cowansage K & Mayford M (2012). Retrieval of contextual fear by optogenetic reactivation of a stable cortical representation. Society for Neuroscience Abstracts, 200.08, New Orleans, LA.
Cowansage K & Mayford M (2011). Invited Talk. Re-exposure to a known context induces a refined pattern of cellular activation in bitransgenic mice expressing a novel dual-color fluorescent timer. Molecular and Cellular Cognition Society, Washington, DC.
Cowansage K, Diaz-Mataix L, Monfils M-H & LeDoux JE (2010). Extinction and synapse-specific disruption of Pavlovian fear memories without emotional expression. Society for Neuroscience Abstracts, 914.20, San Diego, CA.
Hoeffer CA, Cain P, Cowansage K, Wong H, Rothermel E & Klann E (2010). Developmental expression of RCAN 1 regulates innate anxiety via inhibition of phosphatase signaling. Society for Neuroscience Abstracts, 265.16, San Diego, CA.
Trinh M A, Kaphzan H, Van Driesche S, Cowansage K, Cavener DR, Darnell JC & Klann E (2010). Enhanced perseverative behaviors in mice lacking the eIF2a kinase PERK: links to schizophrenia. Society for Neuroscience Abstracts, 471.13, San Diego, CA.
Cowansage K, Klann E & LeDoux JE (2009). Stable fear memory phenotypes predict basal differences in CREB. Society for Molecular and Cellular Cognition, Chicago, IL.
Cowansage K, Klann E & LeDoux JE (2009). Pre-training exposure to novelty enhances performance in memory-impaired individuals. Society for Neuroscience Abstracts, 479.24, Chicago, IL.
Cain P, Hoeffer C, Cowansage K, Wong H, Rothermel B & Klann E (2009). RCAN1 regulates general anxiety via inhibition of phosphatase signaling. Society for Neuroscience Abstracts, 343.12, Chicago, IL.
Cowansage K, Bush DEA, Klann E & LeDoux JE (2008) Individual differences in biochemical modulators of fear acquisition, consolidation, and regulation. Society for Neuroscience Abstracts 591.18, Washington, DC
Hoeffer CA, Cowansage K, Arnold EC, Ledoux JE, Moerke N, Wagner G & Klann E (2008). Effects of small molecule inhibition on the interaction between initiation factors eIF4E and eIF4G following associative fear conditioning. Society for Neuroscience Abstracts 591.25, Washington, DC
Monfils M-H, Cowansage K, Klann EK & LeDoux JE (2008). Behavioral blockade of reconsolidation prevents return of fear. Society for Neuroscience Abstracts 591.17, Washington, DC
Cowansage K, Monfils M-H & LeDoux JE (2007). The sound of silence: when the signal for danger is no signal at all. Society for Neuroscience Abstracts. San Diego, CA
Cowansage KK, Monfils M-H & LeDoux JE (2007). The sound of silence: when the signal for danger is no signal at all. Pavlovian Society Abstracts. Austin, TX
Hoeffer CA, Cowansage K, LeDoux, JE, Wagner, G & Klann E (2007). Effects of small molecule inhibition on the interaction between initiation factors eIF4E and eIF4G following fear conditioning. Society for Neuroscience Abstracts. San Diego, CA
Monfils M-H, Cowansage, K, Chao MV & LeDoux JE (2007). Brain-derived neurotrophic factor mediates fear memory consolidation and induces potentiation of thalamo-amygdala synapses. Society for Neuroscience Abstracts. San Diego, CA
Monfils MH, Diaz-Mataix L, Cowansage K, Doyère V, Dębiec J & LeDoux JE (2007). Pavlovian Society Abstracts. Austin, TX.
Cowansage K, Bush DEA, McEwen BS & LeDoux JE (2006). Comparison of the effects of acute swim, restraint and shock stress on fear conditioning. Society for Neuroscience Abstracts 370.6, Atlanta, GA.

Abstracts, Invited Talks & Contributions


Society for Neuroscience
Molecular and Cellular Cognition Society